{"id":9,"date":"2024-06-18T14:12:50","date_gmt":"2024-06-18T14:12:50","guid":{"rendered":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/?page_id=9"},"modified":"2024-06-27T18:52:04","modified_gmt":"2024-06-27T18:52:04","slug":"research","status":"publish","type":"page","link":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n
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Linsey Marr<\/figcaption><\/figure>\n\n\n\n

The PPP DA showcases four theme areas within its research – Jump, Replicate, Spread, and Empower. By design, we will make independent progress on each theme while supporting the exchange of ideas both internally and externally to Virginia Tech.<\/p>\n\n\n\n

Jump<\/summary>\n

Goal: Create machine learning (ML) methods to predict mutations that will enable a virus to shift from an animal host and adapt to infect humans. <\/p>\n\n\n\n

Team members:
<\/strong>Jonathan Auguste, Entomology, virus ecology and pathogenesis
Deb Bhattacharya, Computer Science (CS), protein structure modeling
Luis Escobar, Fish and Wildlife Conservation, disease ecology and biogeography
Anuj Karpatne, CS, knowledge-guided ML
X. J. Meng, Biomedical Sci. and Pathobiology (BSP), virology
T. M. Murali, CS, computational biology<\/p>\n<\/details>\n\n\n\n

Replicate<\/summary>\n

Goal: <\/strong>Use organoid engineering to test human susceptibility to viruses with pandemic potential and understand the life cycle of a virus to devise ways to interrupt its replication. <\/p>\n\n\n\n

Team Members:<\/strong>
Sanket Deshmukh, Chemical Eng. (ChemE), multiscale modeling and integrated ML
Kylene Kehn-Hall, BSP, <\/strong>virology and antiviral discovery
Padma Rajagopalan, ChemE., tissue engineering and 3D organoid models
Webster Santos, Chemistry, drug discovery and design
Paul Skolnik, Virginia Tech-Carilion School of Medicine, infectious disease and clinical trials
James Weger-Lucarelli, BSP, viral evolution and genetics.<\/p>\n<\/details>\n\n\n\n

Spread<\/summary>\n

Goal:<\/strong> Develop models to predict how a virus spreads from one person to another and across populations with the goal of devising methods to prevent transmission. <\/p>\n\n\n\n

Team members:<\/strong>
Lauren Childs, Mathematics, mathematical modeling of infectious disease dynamics
Navid Ghaffarzadegan, Industrial and Systems Eng.; epidemic modeling, system dynamics modeling, simulation-based policy analysis
Linsey Marr, Civil and Environmental Eng., virus transport and fate in the environment
Naren Ramakrishnan, CS, data science and applied ML. <\/p>\n<\/details>\n\n\n\n

Empower<\/summary>\n

Goal: <\/strong>Ethically engage vulnerable communities to equitably shape and effectively communicate pandemic science.  <\/p>\n\n\n\n

Team members:<\/strong>
Julie Gerdes, English, Infectious disease\/outbreak communication
Kathy Hosig, Population Health Sciences, community-based participatory research
Lisa M. Lee, Population Health Sciences and Division of Scholarly Integrity and Research Compliance, bioethics
Patricia Raun, School of Performing Arts, Center for Communicating Science director.  <\/p>\n<\/details>\n","protected":false},"excerpt":{"rendered":"

The PPP DA showcases four theme areas within its research – Jump, Replicate, Spread, and Empower. By design, we will make independent progress on each theme while supporting the exchange Continue Reading →<\/a><\/p>\n","protected":false},"author":456,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/users\/456"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":11,"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":359,"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/pages\/9\/revisions\/359"}],"wp:attachment":[{"href":"https:\/\/wordpress.cs.vt.edu\/pandemicpredictionandprevention\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}