{"id":1433,"date":"2016-04-08T08:52:34","date_gmt":"2016-04-08T12:52:34","guid":{"rendered":"http:\/\/wordpress.cs.vt.edu\/csblog\/?p=1433"},"modified":"2016-04-20T10:23:20","modified_gmt":"2016-04-20T14:23:20","slug":"t-m-murali-and-shiv-kale-present-new-method-to-reconstruct-signaling-pathways","status":"publish","type":"post","link":"https:\/\/wordpress.cs.vt.edu\/csblog\/2016\/04\/08\/t-m-murali-and-shiv-kale-present-new-method-to-reconstruct-signaling-pathways\/","title":{"rendered":"T. M. Murali and Shiv Kale present new method to reconstruct signaling pathways"},"content":{"rendered":"

Understanding the nature of signaling pathways \u2014 networks of molecules in a cell that work together to control a cell\u2019s response to its environment \u2014 is an increasingly important part of biomedical research and helpful, for example, in enhancing our understanding of how cancer cells live or die.<\/p>\n

In a paper, Pathways on demand: automated reconstruction of human signaling networks<\/a>, published in Systems Biology and Applications, a Nature partner journal, T. M. Murali<\/a>, professor in the Department of Computer Science at Virginia Tech, in collaboration with Shiv Kale, a research scientist at the Biocomplexity Institute of Virginia Tech, present a new computational algorithm called PathLinker that automatically reconstructs signaling pathways from a background network of molecular interactions.<\/p>\n

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Read Full Story<\/a><\/p>\n

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\"Shiv
Shiv Kale (left) and T. M. Murali (right)<\/figcaption><\/figure>\n

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Understanding the nature of signaling pathways \u2014 networks of molecules in a cell that work together to control a cell\u2019s response to its environment \u2014 is an increasingly important part of biomedical research and helpful, for example, in enhancing our understanding of how cancer cells live or die. In a paper, Pathways on demand: automated […]<\/p>\n","protected":false},"author":27,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,1],"tags":[],"class_list":["post-1433","post","type-post","status-publish","format-standard","hentry","category-faculty","category-news"],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/posts\/1433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/comments?post=1433"}],"version-history":[{"count":5,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/posts\/1433\/revisions"}],"predecessor-version":[{"id":1636,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/posts\/1433\/revisions\/1636"}],"wp:attachment":[{"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/media?parent=1433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/categories?post=1433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wordpress.cs.vt.edu\/csblog\/wp-json\/wp\/v2\/tags?post=1433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}